TOWARD CULTURAL ONCOLOGY: THE EVOLUTIONARY INFORMATION DYNAMICS OF CANCER



For a given generalized language of interest with a well defined ergodic
source uncertainty H we write

H[K,J,X]

Imposition of invariance of H under a renormalization transform in the
implicit parameter r leads to expectation of both a critical point in K , which
we call K
C , reflecting a phase transition to or from collective behavior across
the entire array, and of power laws for system behavior near K
C . The addition
of other parameters to the system, e.g. some V , results in a ‘critical line’ or
surface K
C(V ).

Let κ = (KC - K)/KC and take χ as the ‘correlation length’ defining
the average domain in r-space for which the information source is primarily
dominated by ‘strong’ ties. We begin by averaging across r-space in terms of
‘clumps’ of length R. Then, taking Wilson’s [60] physical analog as a starting
point, we choose the renormalization relations as

H[KR,JR,X] = f(R)H[K,J,X]
χ(KR, Jr) = ' KJ

R

(3)

with f(1) = 1 and J1 = J, K1 = K. The first of these equations states
that ‘processing capacity,’ as indexed by the source uncertainty of the sys-
tem, the ‘richness’ of the generalized language, grows monotonically as
f (R).
The second just states that the correlation length simply scales as
R. The
first equation significantly generalizes Wilson’s approach. First, since both
H[KR, JR] and H[K, J] are dimensionless, f(R) must itself be dimensionless.
This is most easily done by assuming that we replace
R with R/R0 , where
R0 is some ‘characteristic length’ of the system for which renormalization is
a reasonable procedure. We then set
R0 1, thus measuring in units of R0.
Wilson’s equation (4) states that free energy density remains constant dur-
ing renormalization: If
F [KR, JR] is the free energy of the clumped system,

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