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Axonal morphophysiology................................................... 46

The Hodgkin-Huxley model.................................................48

Magnetic field in axons ....................................................... 52

Electric field in axons..........................................................53

Implications for microtubule function...................................54

No Hall effect in microtubules.................................................54

Microtubule lattice structure....................................................58

Problems in the ferroelectric model of microtubules...............60

GTP hydrolysis and dynamic instability..................................63

The importance of the water microenvironment .....................65

Tubulin C-termini biological function.......................................68

Post-translational modification of tubulin tails.........................71

Tubulin tail defects and cerebral pathology............................73

Processing of information by brain microtubules....................73

Elastic and piezoelectric properties of microtubules...............77

Discussion..............................................................................77

References..........................................................................79



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