The name is absent



64

ther (figure 4.3, red arrow), and with low membrane impedance (high conductance), signals
dissipate more readily. If
x was absent and only Ih was present in rods, not only would
high-pass filtering of input signals be reduced, but signals would dissipate more quickly due
to unopposed h conductance increase (figure 4.3). If only
IKx was present, then the propa-
gation of signals in the network would be weighted to favor larger responses that completely
turn off the Kx conductance. By having both h and Kx conductance, the cell achieves a high
degree of filtering of input signals while minimizing the distortion of signal propagation in
the network that would be a consequence of membrane conductance change.

We demonstrate that Ih filters the light response even when IKx, ICa and other potas-
sium currents are blocked. This is further evidence that both currents are necessary for fil-
tering of input signals to rods. While it has been previously shown
Ih and x cause opposite
conductance changes during a light response, the potential advantage of these complemen-
tary conductance changes has been unclear. Results from our membrane model of the rod
show that the conductance changes from
Ih and IKx do largely cancel one another, and
that the time course of this net conductance change depends on the stimulus flash intensity.
Further, we propose a potential advantage of the complementary conductances may be to
maximize the amount of filtering by voltage gated channels while minimizing any pertur-
bation of signal spread in the rod network. This would allow the cell to optimally spread
signals from illuminated cells into adjacent rods for better use of the synapses between rods
and bipolar cells.



More intriguing information

1. ADJUSTMENT TO GLOBALISATION: A STUDY OF THE FOOTWEAR INDUSTRY IN EUROPE
2. The name is absent
3. The name is absent
4. Regional differentiation in the Russian federation: A cluster-based typification
5. Problems of operationalizing the concept of a cost-of-living index
6. Micro-strategies of Contextualization Cross-national Transfer of Socially Responsible Investment
7. Behaviour-based Knowledge Systems: An Epigenetic Path from Behaviour to Knowledge
8. THE EFFECT OF MARKETING COOPERATIVES ON COST-REDUCING PROCESS INNOVATION ACTIVITY
9. The Composition of Government Spending and the Real Exchange Rate
10. The name is absent
11. The name is absent
12. The name is absent
13. Ruptures in the probability scale. Calculation of ruptures’ values
14. Do the Largest Firms Grow the Fastest? The Case of U.S. Dairies
15. Electricity output in Spain: Economic analysis of the activity after liberalization
16. The Advantage of Cooperatives under Asymmetric Cost Information
17. Distribution of aggregate income in Portugal from 1995 to 2000 within a SAM (Social Accounting Matrix) framework. Modeling the household sector
18. Estimating the Technology of Cognitive and Noncognitive Skill Formation
19. BUSINESS SUCCESS: WHAT FACTORS REALLY MATTER?
20. Performance - Complexity Comparison of Receivers for a LTE MIMO–OFDM System