Cone voltage response
Figure 4.5 : Simulation of feedback from horizontal cell to cone. A step of light is applied to
the cone at t=l, and at t=2, a feedback signal that shifts the voltage activation curve of the
calcium current 10 mV to the left is applied. (A) The inhibitory depolarization is depen-
dent on both the activity of the calcium activation curve and a calcium activated chloride
conductance. (B) Shows the calcium current as a function of time. (C) Shows the calcium
concentration in the cell, modeled with a first order buffering system. (D) Shows the calcium
activated chloride current, which is the end effector causing depolarization in the cone.
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