The name is absent

32         The Rice Institute Pamphlet

antigens with a high antibody response (Kligler et al., 1936, 1940). In this
connection it may be significant that Ray & Sen Gupta (1954) have actually
detected the presence of lipids in the cytoplasm of E. histolytica.

Conclusion

The views advanced by me in this survey may appear to be somewhat
unorthodox, but they only represent deductions which are consistent with
the mass of observational and experimental data on amebiasis that have
accumulated up to date. Though a coherent pattern is emerging, the pic-
ture is by no means clear-cut, for many details are but faintly outlined,
and much work remains to be done before the enigma of host-parasite
relations in amebiasis is fully solved.

REFERENCES

Anderson, H. H., Bostick, W. L. & Johnstone, H. G. 1953. Amebiasis: pathology,
diagnosis and chemotherapy. Springfield, Ill.

Beaver, P. C., Jung, R. C., Read, T. R. & Robinson, T. A. 1956. Experimental
Entamoeba histolytica infections in man. Am. J. Trop. Med. Hyg. 5, 1000.

Boyd, J. S. K. 1957. Dysentery: some personal experiences and observations. Trans.

R. Soc. Trop. Med. Hyg. 51, 471.

Bozicevich, J. 1950. [Discussion of paper by Hussey and Brown (q.υ.)]. Am. J. Trop.
Med. 30, 154.

Bradin, J. L. 1953. Studies on tire production of hyaluronidase by Endamoeba histo-
lytica. Exper. Parasitai. 2, 230.

Brown, J. A. H. & Whitby, J. L. 1955. An immobilization test for amoebiasis. J. Clin.
Path. 8, 245.

Brumpt, E. 1925. Etude sommaire de YEntamoeba dispar, n.sρ., amibe à kystes
quadrinuclées, parasite de l’homme. Pull. Acad. Méd. 94, 943.

Brumpt, E. 1928. Differentiation of tire human intestinal amoebae with four-nucleated
cysts. Trans. R. Soc. Trop. Med. Hyg. 22, 101.

Brumpt, E. 1949. Précis de parasitologie, 6th ed., Paris.

Burrows, R. B. 1957. Endamoeba hartmanni. Am. J. Hyg. 65, 172.

Chandler, A. C. 1955. Introduction to parasitology, 9th ed. New York.

Chandler, A. C. 1957. Interrelations between nutrition and infectious disease in tire
tropics. (Presidential address). Am. J. Trop. Med. Hyg. 6, 195.

Chang, S. L. 1945. Studies on Entamoeba histolytica. V. On the decrease in infectivity
and pathogenicity for kittens of E. histolytica during prolonged cultivation and
restoration of these characters following encystment and direct animal passage.
J. Inf. Dis. 76, 126.

Cole, B. A. & Kent, J. F. 1953. Immobilization of Endamoeba histolytica in vitro by
antiserum produced in the rabbit. Proc. Soo. Exper, Biol. 83, 811.

Craig, C. F. 1927. Observations upon the hemolytic, cytolytic and complement-
binding properties of extracts of Endamoeba histolytica. Am. J. Trop. Med. 7, 225.

Craig, C. F. 1944. The etiology, diagnosis and treatment of amebiasis. Baltimore.
Craig, C. F. & Faust, E. C. 1951. Clinical parasitology, 5th ed. London.
Dale, H. H. & Dobell, C. 1917. Experiments on the therapeutics of amebic dysentery.

J. Pharmacol. 10, 399.

DeLamater, J. N., Michaelson, J. B., Hallman, F. A. & Blumenthal, H. 1954. An
investigation into hyaluronidase as a factor in the mechanism of tissue invasion by
Endamoeba histolytica. Am. J. Trop. Med. Hyg. 3, 1.

Deschiens, R. 1938. Le rôle de la flore bactérienne, associée à Γamibe dysentérique,
dans l’amibiase. Ann. Inst Pasteur, 61, 5.

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