Fig. 15 An electrical circuit diagram describing the current flows across the cell
membrane that are captured in the Hodgkin-Huxley model Schneidman, 2001).
The individual ionic currents are linearly related to the potential according to
Ohm's law,
(81) IK(t)=GK(V,t)[V(t)-EK]
(82) INa(t)=GNa(V,t)[V(t)-ENa]
(83) IL(t) = GL(V,t)[V(t) - EL]
where GK, GNa and GL are the potassium, sodium and leak conductances per unit
area of the membrane and EK, ENa and VL are the corresponding reversal or
equilibrium potentials of each of the ionic species (the potential at which the ionic
concentration gradient is balanced by the electrical potential gradient, and there
is no net flux of the ions of this type).
49
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