The equilibrium potential for given ion could be calculated by the Nernst
equation:
(84)
E
ion
RT
= —ln
FZ
[ Ion] e
[ Ion]i
where R is the gas constant, T is the temperature, F is the Faraday’s constant, Z
is the valence of the ion, [Ion]e and [Ion]i are the ion concentrations in the
extracellular and in the intracellular space.
The voltage-dependent conductances GNa(t) and GK(t) are given by
(85) GNa(t) = GNmaaxfNa(t)
(86)
GK(t)= GKmaxfK(t)
where GNmaax and GKmax are the peak or maximal sodium and potassium
conductances per unit membrane area and fNa(t) and fK(t) are each the
corresponding (instantaneous) fraction of the maximal conductance which is
actually open (or active).
Thus the equation, which describes the membrane potential as a function of all
the currents that flow across it, is
(87)
Cm^v = GNSOx fNa (t)[ ENa - V (t)] + GJm’x f< (t)[ Ek - V (t)]
+GLmaxfL(t)[EL-V(t)]
+Iinjected(t)
The values for some of the parameters are: ENa = +60 mV, GNmaax = 120 mS/cm2,
EK= -93 mV, GKmax = 36 mS/cm2, EL= -60 mV and GLmax = 0.3 mS/cm2.
KK L L
50
More intriguing information
1. Nurses' retention and hospital characteristics in New South Wales, CHERE Discussion Paper No 522. Infrastructure Investment in Network Industries: The Role of Incentive Regulation and Regulatory Independence
3. Graphical Data Representation in Bankruptcy Analysis
4. ESTIMATION OF EFFICIENT REGRESSION MODELS FOR APPLIED AGRICULTURAL ECONOMICS RESEARCH
5. Impact of Ethanol Production on U.S. and Regional Gasoline Prices and On the Profitability of U.S. Oil Refinery Industry
6. The name is absent
7. La mobilité de la main-d'œuvre en Europe : le rôle des caractéristiques individuelles et de l'hétérogénéité entre pays
8. Computing optimal sampling designs for two-stage studies
9. Education as a Moral Concept
10. Evaluation of the Development Potential of Russian Cities