Synthesis and biological activity of α-galactosyl ceramide KRN7000 and galactosyl (α1→2) galactosyl ceramide



Veerapen et al.


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Page 12


Scheme 4.

Reagents and conditions: (a) NIS/TfOH, CH2Cl2, 67%; (b) TBAF, THF, quant; (c) NaOMe/
MeOH, quant; (d) H
2, Pd, MeOH, 80%; (e) C25H51COCl, THF, NaOAc, 78%.

Published as: BioorgMed Chem Lett. 2009 August 01; 19(15): 4288-4291.



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