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synaptic inputs. In regimes where subthreshold stimuli dominate, such as questions
of (proximal) dendritic democratization and resonance, our reduced model reveals
in minutes what the full models require hours or days to simulate. Although there
is no reason to trust our subthreshold integrator on suprathreshold stimuli, we have
demonstrated that simply thresholding the reduced voltage at a number of observation
points has the potential to capture the cell’s full spiking behavior. Further refinement
of this approach holds the promise of bringing morphological specificity to the large
scale network contributions of (Rudolph and Destexhe, 2006) with significantly fewer
compartments than the approach proposed by (Markram, 2006).
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