Deletion of a mycobacterial gene encoding a reductase leads to an altered cell wall containing β-oxo-mycolic acid analogues, and the accumulation of long-chain ketones related to mycolic acids

Deletion of a mycobacterial gene encoding a reductase leads to an altered cell
wall containing β-oxo-mycolic acid analogues, and the accumulation of long-
chain ketones related to mycolic acids

Apoorva Bhatt*ζ Alistair K. Brown*, Albel Singh, David E. Minnikin and Gurdyal S. Besra

School of Biosciences, University of Birmingham, Edgbaston, Birmingham B15 2TT, U.K.

*These authors contributed equally

^t Correspondence:

Tel: +44-(0)121-4158123, Fax: +44-(0)121-4145925, E-mail: [email protected]

Running Title: Mycobacterial mycolic acid reductase

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