The name is absent

KINETICS ON THE MICROBIAL SCALE

ASSUME (I₀) , PYRUVATE , IS A FIXED INPUT PARAMETER

r * f₂(I, )(I₉)- ⅛(1₂)

fig.7-Determinacy in the krebs cycle and in
IN THE ENTIRE REACTION SYSTEM

Presumably there is an enzyme factory which can synthesize I₈ at
arbitrarily small rate r√ I₈ is also lost by diffusion from the system at
rate MI₈, where M is a small mass transfer coefficient. The steady state
value for l₈, r_s∕M, is the ratio of two small numbers, and can presumably
be whatever the cell desires. The important fact is that the overall rate

FIG. 8- MODIFIED KREBS

CYCLE (SIMPLIFIED)

r is directly proportional to r_s∕M in the steady state.

Since normally M would be fixed by cell morphology, the overall rate
of ATP formation can be controlled by the cell merely by changing the
small rate r_s. This is the principle of the power amplifier and is charac-
teristic of cyclic reaction paths. It will be the subject of a demonstration
in the next paper.

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