The name is absent

Autism prodrome 24 of 89

More specifically, they emphasized that although more SIBS-A than SIBS-TD had
difficulties with transitions, 'difficulty with transitions' should be considered a
potential risk marker and evaluated only in combination with other risk markers for
ASD.

Rebecca Landa and her group are also among the first investigators who
initiated a prospective study of 6-month old infants SIBS-A and infants with no
family history of autism. At 24 months, participants were classified into an ASD
group, LD (language delayed) group, and an unaffected group. The ASD group had
the slowest developmental trajectory, with a significant decrease in development
between 14 and 24 months. Whereas at age 6 months, no significant differences
emerged among the three groups on the Mullen Scales of Early Learning (MSEL;
Mullen, 1995), at 14 months the ASD group performed significantly poorer than the
unaffected group on the MSEL domains with the exception of Visual Reception
domain. By 24 months, the ASD group performed significantly poorer than the
unaffected group on all the MSEL scales and significantly poorer than the LD group
on the Gross and Fine Motor and Receptive Language scales (Landa & Garrett-
Mayer, 2006). In their next report, Landa, Holman and Garrett-Mayer (2007) further
extended their report on the social and communication development of the SIBS-A
and siblings with no family history of autism. This time, participants were classified
into the following groups at 30 or 36 months: ASD group (with two subgroup of
early/late diagnosis), BAP group, and non-BAP group. Results indicated that the
siblings in the ASD early diagnosis subgroup differed at ages of 14 and 24 months
from all other groups, in their communication and play behavior, as measured by the
Communication and Symbolic Behavior Scale - Developmental Profile (CSBS-DP;
Wetherby, Allen, Cleary, Kublin, & Goldstein, 2002). Similar to their previous

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