fMRI Investigation of Cortical and Subcortical Networks in the Learning of Abstract and Effector-Specific Representations of Motor Sequences



L

76

-20

-49

60

7.5

98

-24

-56

53

5.89

Inferior Parietal Lobule (BA 40)

R

44

32

-38

50

3.52

23

36

-31

35

3.99

L

262

-44

-36

52

4.28

289

-48

-33

40

6.21

Precuneus (BA 7)

R

79

20

-52

54

4.92*

9

20

-52

56

4.28*

L

126

-20

-56

53

8.34*

64

-20

-54

54

4.98*

Primary Motor Cortex (BA 4)

L

13

-51

-16

34

4.01

17

-59

-19

40

4.27

Sensory (BA 2/3)

L

143

-44

-29

51

4.31

169

-48

-26

31

6.71

Premotor (dorsal) (BA 6)

R

4

----

12

28

4

40

7.47

L

18

-30

-2

41

4.78

45

-32

4

40

7.81

Premotor (ventral) (BA 6)

R

2

----

0

----

L

13

-53

2

31

2.98

63

-42

-1

28

5.45

Middle Frontal Gyrus (BA 9/46)

R

14

44

8

35

3.82

0

----

L

0

----

26

-48

6

35

5.73

Stereotaxic Talairach coordinates of peak activation obtained with p < .005 (uncorrected). Coordinates of peak
activation are reported for regions having atleast 5 significant voxels. * indicates that the peak was identified using a
ROI mask as clusters of activations spanned across several brain regions.

Table 2b. Locations of significant BOLD signal in the early and late stages of motor > normal contrast

EARLY

LATE

Cluster

Brain area                                size

(voxels)

Middle Temporal Gyrus (BA 39) R     7

Coordinates (mm)

xy  z

51       -63       25

Coordinates (mm)

Cluster size

T value                                 T value

(voxels)

x  yz

3.24                                ---

Superior Parietal Cortex (BA 7)   L 15

-21       -61        55

3.19        10       -34     -54    51    3.8

Inferior Parietal Lobule (BA 40) L 7+4

-36      -42       46

3.3         23       -46     -37    39   3.63

Stereotaxic Talairach coordinates of peak activation obtained with p < .005 (uncorrected).

14



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