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remedy for this is to augment the snapshot set with extra snapshots generated by
giving inputs to these “dead branches” in order to more accurately capture their
dynamics. We have found this to yield significant improvements for some cells, though
our selection of the branches to stimulate has been ad hoc; developing an automated
algorithm for this process will be part of our future work.
Synaptic conductances can also be treated via AMPA, GABA, and NMDA recep-
tors, and their implementation in the reduced model is straightforward. The DEIM
can even be used to reduce the dimension of the voltage-dependent NMDA receptor,
as we have done in preliminary codes.