Deletion of a mycobacterial gene encoding a reductase leads to an altered cell wall containing β-oxo-mycolic acid analogues, and the accumulation of long-chain ketones related to mycolic acids



Shi, J., Blundell, T.L., and Mizuguchi, K. (2001). FUGUE: sequence-structure homology
recognition using environment-specific substitution tables and structure-dependent gap penalties.
J. Mol. Biol.
310, 243-257.

Snapper, S.B., Melton, R.E., Mustafa, S., Kieser, T., and Jacobs, W.R., Jr. (1990). Isolation and
characterization of efficient plasmid transformation mutants of
Mycobacterium smegmatis. Mol.
Microbiol.
4, 1911-1919.

Stover, C.K., de la Cruz, V.F., Fuerst, T.R., Burlein, J.E., Benson, L.A., Bennett, L.T., Bansal,
G.P., Young, J.F., Lee, M.H., Hatfull, G.F.
, et al. (1991). New use of BCG for recombinant
vaccines. Nature
351, 456-460.

Takayama, K., Wang, C., and Besra, G.S. (2005). Pathway to synthesis and processing of
mycolic acids in
Mycobacterium tuberculosis. Clin. Microbiol. Rev. 18, 81-101.

Villeneuve, M., Kawai, M., Watanabe, M., Aoyagi, Y., Hitotsuyanagi, Y., Takeya, K., Gouda,
H., Hirono, S., Minnikin, D.E. and Nakahara, H. (2007). Conformational behavior of oxygenated
mycobacterial mycolic acids from
Mycobacterium bovis BCG. Biochim. Biophys. Acta 1768,
1717-1726.

Walker, R.W., Prome, J.C., and Lacave, C.S. (1973). Biosynthesis of mycolic acids. Formation
of a C
32 beta-keto ester from palmitic acid in a cell-free system of Corynebacterium diphtheriae.
Biochim. Biophys. Acta
326, 52-62.

Wick, L.Y., Wattiau, P., and Harms, H. (2002). Influence of the growth substrate on the mycolic
acid profiles of mycobacteria. Environ. Microbiol.
4, 612-616.

25



More intriguing information

1. The name is absent
2. The name is absent
3. Optimal Tax Policy when Firms are Internationally Mobile
4. If our brains were simple, we would be too simple to understand them.
5. Protocol for Past BP: a randomised controlled trial of different blood pressure targets for people with a history of stroke of transient ischaemic attack (TIA) in primary care
6. Performance - Complexity Comparison of Receivers for a LTE MIMO–OFDM System
7. The name is absent
8. Economic Evaluation of Positron Emission Tomography (PET) in Non Small Cell Lung Cancer (NSCLC), CHERE Working Paper 2007/6
9. Ongoing Emergence: A Core Concept in Epigenetic Robotics
10. The name is absent