Deletion of a mycobacterial gene encoding a reductase leads to an altered cell wall containing β-oxo-mycolic acid analogues, and the accumulation of long-chain ketones related to mycolic acids



Whole Cell

Delipidated

FAMES

MAMEs


α
a’


. epoxy

UFAMEs


MAMEs


mc2155


FAMES

/∕7

2


ΔMSMEG4722


ΔMSMEG4722-C


Whole Cell


Delipidated


FAMEs

MAMEs


MAME-II
a
a’
epoxy


MAME-I

//

V


√i> η?
W
V √?

V



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