Deletion of a mycobacterial gene encoding a reductase leads to an altered cell wall containing β-oxo-mycolic acid analogues, and the accumulation of long-chain ketones related to mycolic acids



A


В


3000-


935.6


2000-



963.6


-(CH2)n-


907.6 |l

Solvent


1000 -




7 4,9,14


6


0--1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1---------1--------1---------1---------1---------1---------1---------1—

750          800          850          900          950         1000         1050

m∕z

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9.0    8.5    8.0    7.5    7.0    6.5    6.0    5.5    5.0    4.5    4.0    3.5    3.0    2.5    2.0     1.5    1.0    0.5    0.0   -0.5

РРт






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