Direct observations of the kinetics of migrating T-cells suggest active retention by endothelial cells with continual bidirectional migration

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Direct observations of the kinetics of migrating T-cells suggest active retention by
endothelial cells with continual bidirectional migration

Helen M. McGettrick¹, Kirsty Hunter¹, Paul A. Moss², Christopher D. Buckley³ G. Ed Rainger,
Gerard B. Nash¹

¹Division of Medical Sciences, ²Division of Cancer Studies and ³Division of Immunity and

Infection, The Medical School, The University of Birmingham, Birmingham, B15 2TT, UK

Running title: Kinetics of T-cell migration

All correspondence to: Professor G.B. Nash

Department of Physiology,

The Medical School

The University of Birmingham

Birmingham B15 2TT

UK

Tel: 00 44 (0)121 414 3670

Fax: 00 44 (0)121 414 6919

Email: [email protected]

Keywords: Lymphocytes, adhesion, flow, cytokines

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