The name is absent

R. D. Oades et al.

PARTIAL CORRELATIONS FOR THREE GROUPS OF
PERSONALITY TRAITS (HANES N1, E1, E2)WITH CB
(FIRST TRIAL MEASURE) IN FOUR SUBJECT
GROUPS

Figure 5. Partial correlations from a linear regression of HANES personality traits with the first trial CB measure.
Increases of Nl (neuroticism and lability) in the NP group (p = .04) and E2 (Outgoingextroverted activity) in the
OCD group were associated with increased CB (p = .002). In PH patients decreased CB was associated with
increases of NI (p= .025) and E2 (p = .063).

not described by a particular symptom. This section examines whether monoamine activity
and the effects of medication are appropriate candidates. Briefly, the biochemical analysis
(see Oades et al., 1994) showed high levels of utilization (metabolite∕monoamine) in PH
and NP vs comparison groups for DA, NA and 5HT, where DA utilization tended to be
higher in PH patients. OCD patients showed increased levels of adrenalin, HVA, 5HT and
5HIAA.

Medication

Neuroleptic doses did not correlate with CB or biochemical measures, except for an
increase in HVA and the HVA∕5HIAA ratio in the PH group alone (r= + .58, p= .04). Of
five patients taking clozapine (four in the PH group) two showed good CB and two showed
some attenuation. These patients did not show increased NA utilization as might be
expected from α-2 anatagonism. However, two patients on propranolol had high MHPG
levels and were excluded from the analysis. Patient groups did not differ significantly on
anticholinergic medication [biperidine: PH, n = 8, mean 4.3 mg (52)=1.7 mg); NP n = 6,
mean 5.3 mg (SD = 1.6)]. However, as dose tended to relate to BA 1-3 and BA 1-5
(r= + .46-.51, .05<∕><.l) a cholinergic influence on CB should not be overlooked.

Associations with Monoamine Metabolism

Among adrenergic measures only NA utilization (MHPG∕NA) correlated with any CB
measure (CON alone, BA 1 and BA 1-3, r = +.52-.42, p = .01-.02). However, in OCD

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