36
Table 2.4: Probability of different toxicities (at any grade; rows) conditional on the
same patient having experienced other toxicities (at any grade; columns). The two
numbers x/у in each cell report probabilities under placebo∕isotretinoin. For com-
parison the diagonal reports in bold the marginal probabilities of exhibiting each type
of toxicity.
Abnormal |
Arthralgia |
CheiIitis |
Conjunctivitis |
Fatigue |
Headache |
Hyper- | |
vision (AV) | |||||||
AV |
0.026/0.028 |
0.175/0.186 |
0.071/0.043 |
0.108/0.099 |
0.171/0.209 |
0.249/0.266 |
0.078/0.11 |
AR |
0.428/0.518 |
0.063/0.078 |
0.12/0.107 |
0.162/0.199 |
0.227/0.316 |
0.326/0.391 |
0.134/0.201 |
CH |
0.533/0.923 |
0.366/0.821 |
0.192/0.602 |
0.302/0.824 |
0.348/0.774 |
0.442/0.823 |
0.334/0.729 |
CO |
0.438/0.78 |
0.267/0.566 |
0.163/0.305 |
0.104/0.223 |
0.256/0.511 |
0.344/0.603 |
0.176/0.411 |
FA |
0.223/0.306 |
0.121/0.166 |
0.061/0.053 |
0.082/0.095 |
0.033/0.041 |
0.168/0.238 |
0.061/0.105 |
HE |
0.366/0.304 |
0.195/0.161 |
0.087/0.044 |
0.125/0.087 |
0.189/0.186 |
0.038/0.032 |
0.095/0.098 |
HT |
0.089/0.581 |
0.062/0.382 |
0.051/0.181 |
0.049/0.275 |
0.053/0.381 |
0.074/0.456 |
0.029/0.149 |
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