Autism prodrome 85 of 89
Table 2 (continued)
Prospective screening studies
Reference |
Age (Months) |
Study design |
Administration |
Key items/content |
Instrument parameters | |
Robins et al. (2001); Kleinman et al. (2008)_________ |
M- CHAT |
24m |
Combined high-risk: early screening (n = 3,309)_________ |
Parent questionnaire |
Most discriminating items: joint attention behaviors and social relatedness |
Positive predictive value = 36% |
Wetherby et al. (2004, 2008) |
Ict |
9-24m |
Population screening (n = |
Parent questionnaire |
Early social communication behaviors; emotional response |
Positive and negative predictive |
Reznik et al. (2007); Watson et al. (2007) |
^^FYI |
12m |
Pilot population study (n = |
Parent questionnaire |
Full range of possible early |
Follow-up studies not yet conducted |
CHAT (Checklist for Autism in Toddlers); ESAT (Early Screening of Autistic Traits); M-CHAT (Modified- Checklist for Autism in Toddlers); ITC (Infant
Toddler Checklist); FYI (First Year Inventory)