The name is absent



Autism prodrome 87 of 89

Table 3 (continued)

High risk sibling studies

Reference

N

(SIBS-A)

Age

(Months)

Comparison

group

Findings

Landa & Garrett-

Mayer (2006)

60

6-24m

TD n =27

At 6m no significant differences emerged among the three groups (ASD, LD, unaffected
diagnosed at 24m) on the MSEL. At 14m the ASD group performed significantly poorer than the
unaffected group on most of the MSEL scales. By 24m the ASD group performed significantly
poorer than the unaffected group on all the MSEL scales and significantly poorer than the LD
group on the Gross and Fine Motor and Receptive Language scales. ASD group had the slowest
developmental trajectory, with a significant decrease in development between 14m and 24m

Landa et al. (2007)

98

14-36m

TD n =17

The ASD early diagnosis subgroup differed at ages of 14m and 24m from all other groups (ASD
with late diagnosis, BAP, and non-BAP) in their communication and play behavior.________________

Nadig et al. (2007)

Table 3 (continued)

46

6-24m

TD n =25

At 6m no significant differences emerged between siblings and controls in orienting to name.

However, at 12m all controls oriented to calling their name compared to 86% of the siblings. 75%
of the siblings who failed to respond to their name being called were identified at age 24m with
ASD or with other developmental delays.

High risk sibling studies



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