Autism prodrome 88 of 89
|
Reference |
N
(SIBS-A) |
Age
(Months) |
Comparison
group |
Findings |
|
Merin et al. (2007) |
31 |
6m |
TD n =24 |
10 of the 11 infants with diminished gaze to the mother’s eyes relative to her mouth during the Still
Face were SIBS-A. No significant differences emerged between the two groups in affective
displays (i.e., smiling, negative affect), in the total amount of fixation time, or in the fixation
directed at the face versus other areas |
|
Young et al. (2009) |
33 |
6-24m |
TD n =25 |
All three siblings with ASD at 24m (2 SIBS-A, 1 SIBS-TD) demonstrated consistent eye contact
and typical affective responses at 6m during the Still face. No associations were found between
face scanning and affective responses at 6m and the continuous measures of autism symptom
frequency or symptom severity at 24m. Diminished gaze to the mother’s eyes relative to her mouth
at 6m predicted higher scores of expressive language at 24m |
|
Ozonoff et al.
(2008) |
35 |
12-36m |
TD n =31 |
Siblings with later ASD had increased frequency of spinning, rolling and rotating the objects and
prolonged visual inspection at 12m. Repetitive behaviors at 12m were significantly related to
cognitive and symptomatic status at the 36m outcome |
Table 3 (continued)
High risk sibling studies
|
Reference |
N
(SIBS-A) |
Age
(Months) |
Comparison
group |
Findings |