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127

Variables and Constants

V

Membrane voltage (mV)

i

Currents given in pA

Cm = 35 ■ 10^3 nF
gc = 0.5 nS

9kx ~ 1∙5 ɪɪs

Ekx = -74 mV

9h = 2 nS

gkυ = 0.5 nS

Eh = -30 mV

Ekv = -74 mV

9leak — 0.2 nS

9ca = 2 nS

Idark ~~ 50 pA

Eieak = -55 mV

Eca - 40 mV

Photocurrent (from Hamer, 2000)

F = (cG∕cGdarkffca

R = Φ-(1∕tr)R

È = υrp(R- (l∕τ⅛)E,)

Normalizeddarkcurrentfraction

Rhodopsin activation rate

Phosphodiesterase activation rate

cG = Amax∕(l + (c∕(Kcα)ncα) - cG(βdark + Eβff)            cGMP activation rate

Outer Segment Calcium Concentration and BufferActivity

c = bJdF - 7c(c- cmm) - Cb                   Change in calcium concentration

Cb = ⅛ι(ei - cβ)c - ∕⅞<¾                                Change in buffered calcium



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