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129


h-current kinetics

nh = 1 - ((1 - mhy + 4mh(l - m⅛)3)
mh = ah(l - mh) - βhmh

ан - 18/(1 + exp((v + 88)/12))

βh = 18/(1 + exp(-(v + 18)/19))


Probability of ≥ 2 of 4 particles being open

Probability of one particle being open


kx-current kinetics

∏^kx ~ ɑfeæ(l ^ʃɪfeʃ) βkx^kx
akx = 0.66exp ((υ + 50)/(2 ■ 5.7))
∕3fcτ = 0.66 exp (-(υ + 50)/(2 ■ 5.7))


Two-state noninactivating kinetics


kv-current kinetics

τ⅛υ = r∏l,υhkv                              Gating with 3 activation and 1 inactivation particles

τrikυ = amkv ( 1 - mmkυ ) - βmkυmmkυ                                       Activation particle

amkv = 5(100 - 77)∕exp((lOO - t>)∕42) - 1)

βmkυ = 9exp(-(z? - 20)/40)

hkυ ~ ɑftfet)(l hkυ) βhkvhkv

Inactivation particle


ahkv = 0.15exp(-w∕22)

βhkυ = 0.4125/exp(-(t> - 10)/7 + 1)



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